CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 31 enrolled
Drug / intervention
Protein powder supplement, standard dosage based on 0.5 gram protein per pound of subject's lean body mass +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT01146704
NCT01146704N/ACompleted
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Gastrointestinal Hormonal Regulation of Obesity

VA Office of Research and Development·interventional·Posted Jun 17, 2010·Updated Feb 4, 2025

In Brief

A clinical study evaluating Protein powder supplement, standard dosage based on 0.5 gram protein per pound of subject's lean body mass and Protein powder supplement, High Level Protein, based on 1 gram of protein per pound of lean body mass: 25% protein and 45% carbohydrate for Obesity. Completed, enrolled 31 participants across 1 site.

Detailed Summary

The objective of this study is to test and determine whether a high protein diet is efficacious, safe and beneficial to curtail food intake and body weight in obese adult human patients and to establish whether neurohormonal mechanisms of a high protein diet induce an early signal of fullness or satiety in a relevant experimental model, focusing on activation of gastric vagal afferents.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObesity
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJun 17, 2010
Enrollment StartSep 1, 2010
Primary CompletionDec 31, 2018
Study CompletionFeb 27, 2019
TodayJul 2, 2026
Enrollment to primary: 8.3 yearsPosted 16.0 years ago

Interventions

Protein powder supplement, standard dosage based on 0.5 gram protein per pound of subject's lean body massdietary

Standard protein diet as control, based on 0.5 gram protein per pound of lean body mass, isocaloric (same number of calories) and consisting of 15% protein and 55% carbohydrate.

Protein powder supplement, High Level Protein, based on 1 gram of protein per pound of lean body mass: 25% protein and 45% carbohydratedietary

High level of protein diet, based on 1 gram of protein per pound of subject's lean body mass, isocaloric (same number of calories) and consisting of 30% protein and 40% carbohydrate.