CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 800 enrolled
Drug / intervention
maintain mean arterial pressure between 80-85 mm Hg +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01149278
NCT01149278N/ACompleted
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Assessment of Two Levels of Arterial Pressure on Survival in Patients With Septic Shock

University Hospital, Angers·interventional·Posted Jun 23, 2010·Updated Nov 5, 2012

In Brief

A clinical study evaluating maintain mean arterial pressure between 80-85 mm Hg and maintain mean arterial pressure between 65-70 mm Hg for Septic Shock and 4 related conditions. Completed, enrolled 800 participants across 1 site.

Detailed Summary

The ideal mean arterial pressure in patients with septic shock is unknown. The expert's recommandations have stated a target between 65 and 70 mm Hg. However the scientific basis are weak. Indead there are only few prospective studies which addressed this question without clear answer. Therefore we designed a RCT in order to assess the effect on mortality of two levels of mean arterial pressure in patients with septic shock.(800 patients, 30 centres)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSeptic Shock, Arterial Pressure, Hemodynamics, Mortality, Clinical Trial
CountriesFrance
Collaborators--

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedJun 23, 2010
Enrollment StartMar 1, 2010
Primary CompletionSep 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 16.0 years ago

Interventions

maintain mean arterial pressure between 80-85 mm Hgdrug

protocolized hemodynamic care aiming to maintain mean arterial pressure between 80-85 mm Hg

maintain mean arterial pressure between 65-70 mm Hgother

protocolized hemodynamic care aiming to maintain mean arterial pressure between 65-70 mm Hg