CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 31 enrolled
Drug / intervention
Bilevel PAP (4 weeks) +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01154699
NCT01154699N/ACompleted
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Positive Airway Pressure for the Treatment of Asthma

Brigham and Women's Hospital·interventional·Posted Jul 1, 2010·Updated May 17, 2017

In Brief

A clinical study evaluating Bilevel PAP (4 weeks), Usual Care (4 weeks), and 1 other intervention for Asthma and Sleep Apnea. Completed, enrolled 31 participants across 1 site.

Detailed Summary

Asthma is an extremely common disorder, which is becoming more prevalent. The purpose of this study is to examine how nocturnal lung volumes contribute to asthma severity, which may explain part of the link between asthma and obesity. The investigators seek to test the hypothesis that raising lung volumes during the night will improve asthma symptoms. The investigators work may lead to new targets for therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma, Sleep Apnea
CountriesUnited States
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI)

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJul 1, 2010
Enrollment StartJul 1, 2010
Primary CompletionSep 1, 2014
Study CompletionDec 1, 2014
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 16.0 years ago

Interventions

Bilevel PAP (4 weeks)device

Subjects will use bilevel PAP each night for 4 weeks. The pressure levels will be adjusted by the investigators to increase lung volumes during the night.

Usual Care (4 weeks)other

Subjects will continue with their usual asthma care. Investigators will make no changes to their medications or other habits.

Washout Period (4 weeks)other

Subjects will continue with their usual asthma care in between the Usual Care and Bilevel PAP periods. Investigators will make no changes to their medications or other habits.