At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 28 enrolled
Drug / intervention
pazopanib hydrochloride +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase II Study of Pazopanib in VEGF-TKI Refractory Metastatic Renal Cell Carcinoma (MRCC)
In Brief
A Phase 2 clinical trial evaluating pazopanib hydrochloride, laboratory biomarker analysis, and 1 other intervention for Clear Cell Renal Cell Carcinoma and 2 related conditions. Completed, enrolled 28 participants across 2 sites.
Detailed Summary
RATIONALE: Pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying how well pazopanib hydrochloride works in treating patients with stage IV kidney cancer.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJul 2010
Enrollment StartDec 2010
Primary CompletionOct 2013
Study CompletionDec 2013
TodayJul 2026
First PostedJul 5, 2010
Enrollment StartDec 8, 2010
Primary CompletionOct 17, 2013
Study CompletionDec 31, 2013
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 16.0 years ago
Interventions
pazopanib hydrochloridedrug
Given orally
laboratory biomarker analysisother
Correlative studies
immunologic techniqueother
Correlative studies