At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 33 enrolled
Drug / intervention
D-cycloserine +2 moredrug
Likely dose
D-cycloserine 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of D-cycloserine on Treatment of PTSD in Youth
In Brief
A Phase 2 clinical trial evaluating D-cycloserine, Placebo pill, and 1 other intervention for Posttraumatic Stress Disorders and PTSD. Completed, enrolled 33 participants across 1 site.
Detailed Summary
The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 7-12 year old children.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPosttraumatic Stress Disorders, PTSD
CountriesUnited States
CollaboratorsNational Institute of Mental Health (NIMH)
Timeline
Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartJun 2010
First PostedJul 2010
Primary CompletionJun 2012
TodayJul 2026
First PostedJul 7, 2010
Enrollment StartJun 1, 2010
Primary CompletionJun 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 16.0 years ago
Interventions
D-cycloserinedrug
D-cycloserine 50 mg by mouth prior to sessions 5-12 of the 12-session CBT protocol.
Placebo pilldrug
Placebo pill by mouth prior to sessions 5-12 of the 12-session CBT protocol.
CBTbehavioral
12-session CBT protocol, called Youth PTSD Treatment.