CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 24 enrolled
Drug / intervention
D-cycloserine +2 moredrug
Likely dose
D-cycloserine 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01157429
NCT01157429Phase 2Completed
CompareCT.gov

D-cycloserine Adjunctive Treatment for PTSD in Adolescents

Tulane University School of Medicine·interventional·Posted Jul 7, 2010·Updated Jun 6, 2017

In Brief

A Phase 2 clinical trial evaluating D-cycloserine, Placebo pill, and 1 other intervention for Posttraumatic Stress Disorder and PTSD. Completed, enrolled 24 participants across 1 site.

Detailed Summary

The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 13-18 year-old children.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPosttraumatic Stress Disorder, PTSD
CountriesUnited States
CollaboratorsNational Alliance for Research on Schizophrenia and Depression

Timeline

Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedJul 7, 2010
Enrollment StartJun 1, 2010
Primary CompletionJun 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 16.0 years ago

Interventions

D-cycloserinedrug

D-cycloserine 50 mg by mouth prior to sessions 5-12 of the 12-session CBT protocol.

Placebo pilldrug

Placebo pill by mouth prior to sessions 5-12 of teh 12-session CBT protocol.

CBTbehavioral

12-session CBT protocol, called Youth PTSD Treatment.