CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 160 enrolled
Drug / intervention
Nerve Block +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01163214
NCT01163214Phase 4Completed
CompareCT.gov

Prospective Randomized Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Postoperative Pain After Total Knee Replacement.

Mark J. Spangehl, M.D.·interventional·Posted Jul 15, 2010·Updated Nov 5, 2014

In Brief

A Phase 4 clinical trial evaluating Nerve Block and Periarticular Injection for Postoperative Pain and Knee Replacement Arthroplasty. Completed, enrolled 160 participants across 1 site.

Detailed Summary

The purpose of this study is to compare two methods of postoperative pain management in patients undergoing total knee replacement.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPostoperative Pain, Knee Replacement Arthroplasty
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJul 15, 2010
Enrollment StartJul 1, 2010
Primary CompletionJun 1, 2013
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 16.0 years ago

Interventions

Nerve Blockdrug

Regional anesthetic nerve block using an indwelling femoral nerve catheter and a single shot sciatic nerve block using 0.5% ropivacaine.

Periarticular Injectiondrug

Periarticular local injection into the periarticular soft tissues at the time of knee replacement using a combination of ropivacaine, epinephrine, ketorolac, and morphine sulphate. Subjects in this arm received the injection combination based on three subject weight categories.