CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 57 enrolled
Drug / intervention
Ascorbic Acid +1 moredrug
Likely dose
Ascorbic Acid 10mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01167569
NCT01167569Phase 4Completed
CompareCT.gov

Double-Blind, Randomized Study of High Dose Vitamin C On Outcome in Cardiac Surgery Patients

Rutgers, The State University of New Jersey·interventional·Posted Jul 22, 2010·Updated Oct 19, 2020

In Brief

A Phase 4 clinical trial evaluating Ascorbic Acid and 5 % Dextrose Water or Normal Saline for Reperfusion Injury. Completed, enrolled 57 participants across 1 site.

Detailed Summary

It has been shown that the stress that occurs during cardiac surgery leads to early decrease of many of the body's resources such as Vitamin C (ascorbic acid) which may contribute to complications after surgery. This study will investigate the effects of high doses of intravenous (IV) Vitamin C on the outcome and complications after cardiac surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsReperfusion Injury
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJul 22, 2010
Enrollment StartOct 1, 2007
Primary CompletionApr 1, 2013
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 15.9 years ago

Interventions

Ascorbic Aciddrug

Ascorbic Acid/Placebo 10mg/kg body weight X2 in Operating Room followed by Ascorbic Acid/Placebo 5mg/kg x 48 hours.

5 % Dextrose Water or Normal Salineother

100 ml D5W or NS X 2 in operating room and then every 4 hours for 48 hours.