CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled
Drug / intervention
D-cycloserine +1 moredrug
Likely dose
D-cycloserine 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01172873
NCT01172873N/ACompleted
CompareCT.gov

Open-Label Exploratory Investigation of D-Cycloserine Augmentation to Cognitive Behavioral Therapy With Exposure and Response Prevention for Adults and Adolescents Diagnosed With Obsessive Compulsive Disorder - A Feasibility Study

New York State Psychiatric Institute·interventional·Posted Jul 30, 2010·Updated Aug 19, 2014

In Brief

A clinical study evaluating D-cycloserine and Exposure and Response Prevention (EX/RP) for Obsessive Compulsive Disorder. Completed, enrolled 16 participants across 1 site.

Detailed Summary

This is a single site, open-label, feasibility study of cognitive behavioral therapy with exposure and response prevention (CBT/ERP) adding the augmentation of D-cycloserine (DCS) for adolescents ages 12-17 with Obsessive Compulsive Disorder (OCD) who are partial or non-responders to first line treatments of CBT or pharmacotherapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObsessive Compulsive Disorder
CountriesUnited States
CollaboratorsEmory University

Timeline

N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedJul 30, 2010
Enrollment StartSep 1, 2008
Primary CompletionSep 1, 2010
Study CompletionDec 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 15.9 years ago

Interventions

D-cycloserinedrug

50 mg dose of D-cycloserine administered at the end of each session of Cognitive Behavioral Therapy With Exposure and Response Prevention: twice weekly CBT/ERP of 60 minutes

Exposure and Response Prevention (EX/RP)behavioral

Exposure and response prevention treatment. Participants complete graded exposure during twice weekly treatment sessions with therapist