At a glance
ClinicalIndex Comparison RecordN/ACompleted· 110 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Epigenetic Regulation of Brain-Derived Neurotropic Factor (BDNF) in Patients With Major Depression
In Brief
An observational study for Major Depressive Disorder. Completed, enrolled 110 participants across 1 site.
Detailed Summary
The investigators will (1) detect the associations between brain-derived neurotrophic factor (BDNF) DNA methylation, histone modification, depressive symptoms, suicidal behavior and antidepressant responses in major depressive disorder (MDD) patients, (2) check the correlation between blood BDNF protein and RNA and BDNF rs6265 gene, and (3) discuss the possible mechanisms of epigenetic regulation of BDNF in Taiwanese major depressive patients.
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsMajor Depressive Disorder
CountriesTaiwan
Collaborators--
Timeline
N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
Enrollment StartAug 2010
First PostedAug 2010
Primary CompletionJul 2012
Study CompletionMay 2013
TodayJul 2026
First PostedAug 16, 2010
Enrollment StartAug 1, 2010
Primary CompletionJul 1, 2012
Study CompletionMay 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 15.9 years ago