CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 174 enrolled
Drug / intervention
Linear Aerobic Training +4 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01186367
NCT01186367N/ACompleted

Exercise Intensity Trial (EXCITE): A Randomized Trial Comparing the Effects of Linear Versus Nonlinear Aerobic Training in Women With Operable Breast Cancer

Memorial Sloan Kettering Cancer Center·interventional·Posted Aug 23, 2010·Updated Feb 10, 2025

In Brief

A clinical study evaluating Linear Aerobic Training, Nonlinear Aerobic Training, and 3 other interventions for Breast Cancer. Completed, enrolled 174 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the effects of 3 different approaches to exercise training in women with early stage breast cancer who have completed all primary treatments (except hormone therapy, if appropriate). Prior research in women with early stage breast cancer has shown that some treatments may have an adverse impact on physical fitness levels leading to feelings of fatigue and poor quality of life. Supervised exercise training has been shown to reduce some of these side-effects. However, all the exercise programs have followed essentially the same approach. This study is designed to see if a different approach to exercise training is more effective than the conventional approach currently in use.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBreast Cancer
CountriesUnited States
CollaboratorsDuke University

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedAug 23, 2010
Enrollment StartNov 11, 2010
Primary CompletionMay 17, 2023
TodayJul 2, 2026
Enrollment to primary: 12.5 yearsPosted 15.9 years ago

Interventions

Linear Aerobic Trainingbehavioral

The 130-180 minutes/week will be achieved via either 3 to 4 individual aerobic training sessions at approximately 10 to 50 minutes per/session (± 10 minutes).

Nonlinear Aerobic Trainingbehavioral

The 130-180 minutes/week will be achieved via 3 to 4 individual aerobic training sessions at approximately 10 to 50 minutes/ per session (+/- 10 minutes).

Progressive Stretchingbehavioral

All sessions are required to be supervised. Duration of the stretching sessions is prescribed and implemented in accordance with standard stretching and flexibility training principles. This approach will be applied to guide each participant's prescribed stretching plan, with dose and scheduling modifications made by exercise physiologists, as required.

Cardiopulmonary exercise test (CPET)other

Blood drawsother

Complete blood count