At a glance
ClinicalIndex Comparison RecordN/ACompleted· 63 enrolled
Drug / intervention
Radiation Therapyradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Dose-Reduced Consolidation Radiation Therapy in Patients With Diffuse Large B-cell Lymphoma
In Brief
A clinical study evaluating Radiation Therapy for Diffuse Large B-cell Lymphoma. Completed, enrolled 63 participants across 3 sites.
Detailed Summary
This study will evaluate whether a reduction in the radiation dose and field size will maintain a high rate of local control while minimizing the risk of acute and late toxicity. Hypothesis- The radiation dose and treatment volume can be safely reduced from 30 Gy to 20 Gy while maintaining high rates of local control in patients who had a negative PET scan following rituximab-containing chemotherapy.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDiffuse Large B-cell Lymphoma
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedAug 2010
Enrollment StartSep 2010
Primary CompletionJun 2019
TodayJul 2026
First PostedAug 23, 2010
Enrollment StartSep 20, 2010
Primary CompletionJun 4, 2019
TodayJul 2, 2026
Enrollment to primary: 8.7 yearsPosted 15.9 years ago
Interventions
Radiation Therapyradiation
1.5-2 Gy per fraction to a total dose of 19.8-20 Gy with radiation given 5 days/week