At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 152 enrolled
Drug / intervention
Dexamethasone +1 moredrug
Likely dose
Dexamethasone 8mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Preoperative Single-dose Steroid Application for the Treatment of Nausea and Vomiting After Thyroid Surgery
In Brief
A Phase 3 clinical trial evaluating Dexamethasone and NaCl 0.9% for Thyroidectomy and Thyroid Diseases. Completed, enrolled 152 participants across 1 site.
Detailed Summary
The study is to compare the postoperative recovery, as determined by postoperative nausea and vomiting (PONV) after preoperative application of single-dose dexamethasone versus saline in patients undergoing partial or total thyroidectomy.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsThyroidectomy, Thyroid Diseases
CountriesSwitzerland
Collaborators--
Timeline
Phase 3CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedAug 2010
Enrollment StartJan 2011
Primary CompletionMay 2013
Study CompletionJun 2013
TodayJul 2026
First PostedAug 26, 2010
Enrollment StartJan 1, 2011
Primary CompletionMay 1, 2013
Study CompletionJun 1, 2013
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 15.8 years ago
Interventions
Dexamethasonedrug
8mg (2ml) of dexamethasone (Mephameson®) administered intravenously preoperatively before thyroid surgery
NaCl 0.9%other
2ml of NaCl 0.9% administered intravenously preoperatively before thyroid surgery