At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 246 enrolled
Drug / intervention
Chlorthalidone 25 mg + amiloride hydrochloride 5 mg +1 moredrug
Likely dose
Chlorthalidone 25 mg + amiloride hydrochloride 5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Study to Evaluate the Safety and Efficacy of Chlorthalidone in Combination With Amiloride as a Treatment for Elderly Patients With Arterial Hypertension
In Brief
A Phase 3 clinical trial evaluating Chlorthalidone 25 mg + amiloride hydrochloride 5 mg and Higroton® Laboratório Novartis for Arterial Hypertension. Completed, enrolled 246 participants across 10 sites.
Detailed Summary
The purpose of this study is to assess the efficacy and safety of Chlorthalidone 25 mg + amiloride hydrochloride 5 mg association in the treatment of elderly patients with arterial hypertension.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsArterial Hypertension
CountriesBrazil
Collaborators--
Timeline
Phase 3CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedAug 2010
Enrollment StartAug 2011
Primary CompletionAug 2013
TodayJul 2026
First PostedAug 30, 2010
Enrollment StartAug 1, 2011
Primary CompletionAug 1, 2013
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 15.8 years ago
Interventions
Chlorthalidone 25 mg + amiloride hydrochloride 5 mgdrug
Chlorthalidone 25 mg + amiloride hydrochloride 5 mg - one oral tablet a day in the morning during approximately 12 weeks
Higroton® Laboratório Novartisdrug
Chlortalidone 25mg - oral tablet a day in the morning during approximately 12 weeks