At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 129 enrolled
Drug / intervention
G-CSF +1 moredrug
Likely dose
G-CSF 300 unitsfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
G-CSF(Granulocyte Colony Stimulating Factor) and Embryo Implantation and Pregnancy Following IVF (in Vitro Fertilization)
In Brief
A Phase 2 clinical trial evaluating G-CSF and Saline for Infertility, Female. Completed, enrolled 129 participants across 1 site.
Detailed Summary
This a trial designed to test whether granulocyte colony stimulating factor (G-CSF, Neupogen) can increase the rate of embryo implantation following IVF and embryo transfer. Preliminary data at the Center for Human Reproduction(CHR) and elsewhere suggest that intrauterine infusion of G-CSF can improve endometrial development and can increase implantation rates of embryos.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInfertility, Female
CountriesUnited States
CollaboratorsFoundation for Reproductive Medicine
Timeline
Phase 2CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
Enrollment StartSep 2010
First PostedSep 2010
Primary CompletionDec 2012
Study CompletionJun 2013
TodayJul 2026
First PostedSep 16, 2010
Enrollment StartSep 1, 2010
Primary CompletionDec 1, 2012
Study CompletionJun 1, 2013
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 15.8 years ago
Interventions
G-CSFdrug
One infusion of G-CSF 300 units administered by intrauterine infusion
Salinedrug
intrauterine saline infusion 1 cc