CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 41 enrolled
Drug / intervention
MM-121 +1 moredrug
Likely dose
Paclitaxel 80 mg/m2from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01209195
NCT01209195Phase 1Completed

A Phase 1, Pharmacologic and Pharmacodynamic Study of MM-121 in Combination With Paclitaxel in Patients With Advanced Gynecologic and Breast Cancers

Merrimack Pharmaceuticals·interventional·Posted Sep 27, 2010·Updated Sep 8, 2016

In Brief

A Phase 1 clinical trial evaluating MM-121 and Paclitaxel for Locally Advanced/Metastatic or Recurrent Ovarian Cancer, Fallopian Tube Cancer, and 2 related conditions. Completed, enrolled 41 participants across 5 sites.

Detailed Summary

This study was a Phase 1 and pharmacologic open-labeled dose-escalation trial of MM-121 in combination with paclitaxel using a "3+3" design.

Study Details

Timeline

Phase 1CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedSep 27, 2010
Enrollment StartOct 1, 2010
Primary CompletionMay 1, 2014
Study CompletionJul 1, 2014
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 15.8 years ago

Interventions

MM-121drug

increasing doses of MM-121 IV QW

Paclitaxeldrug

Paclitaxel - 80 mg/m2 IV QW