CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 183 enrolled
Drug / intervention
Prolonged Exposure +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01211106
NCT01211106N/ACompleted

Integrated vs Sequential Treatment for PTSD and Addiction Among OEF/OIF Veterans

VA Office of Research and Development·interventional·Posted Sep 29, 2010·Updated Mar 9, 2017

In Brief

A clinical study evaluating Prolonged Exposure and Motivational Enhancement Therapy for PTSD and Substance Addiction. Completed, enrolled 183 participants across 2 sites.

Detailed Summary

The investigators are examining different treatment strategies of helping patients with PTSD and addiction.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedSep 29, 2010
Enrollment StartFeb 1, 2011
Primary CompletionMar 1, 2016
Study CompletionJul 1, 2016
TodayJul 2, 2026
Enrollment to primary: 5.1 yearsPosted 15.8 years ago

Interventions

Prolonged Exposurebehavioral

Although almost every form of psychotherapy has been advocated for PTSD, all evidence-based psychotherapies for PTSD are CBT programs that include variants of exposure therapy (Prolonged Exposure), cognitive therapy (CT), stress inoculation training (SIT), eye movement desensitization and reprocessing (EMDR), or combinations of these procedures. Exposure therapy involves helping PTSD sufferers to gradually confront distressing trauma-related memories and reminders to facilitate successful emotional processing of the trauma memory and reduction of associated distress. Most exposure therapy programs include both imaginable confrontation with the traumatic memories and in vivo exposure to trauma reminders.

Motivational Enhancement Therapybehavioral

Motivational Interviewing (MI) is defined as a client-centered, directive method for enhancing intrinsic motivation to change by exploring and resolving ambivalence. MI is characterized by its spirit, which is defined as collaboration with the client, evocation of the client's own perceptions, goals, and values, and respect for the client's autonomy.