At a glance
ClinicalIndex Comparison RecordN/ACompleted· 40 enrolled
Drug / intervention
plasmapheresisprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Study of Combinative Effect of Induction Therapy With Mitoxantrone and Plasmapheresis to Treat Patients With Aggressive Multiple Sclerosis
In Brief
A clinical study evaluating plasmapheresis for Multiple Sclerosis. Completed, enrolled 40 participants across 1 site.
Detailed Summary
The purpose of this study is to compare the effect of combinative induction therapy with mitoxantrone and plasmapheresis versus induction therapy with mitoxantrone alone in cases of aggressive multiple sclerosis
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMultiple Sclerosis
CountriesIran
Collaborators--
Timeline
N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartJan 2010
First PostedOct 2010
Primary CompletionJan 2012
Study CompletionFeb 2012
TodayJul 2026
First PostedOct 5, 2010
Enrollment StartJan 1, 2010
Primary CompletionJan 1, 2012
Study CompletionFeb 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 15.7 years ago
Interventions
plasmapheresisprocedure
3 courses of plasmapheresis are performed before mitoxantrone injection in first 3 months to investigate the efficacy of plasmapheresis in comparison with the other arm that are only treated with mitoxantrone