CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 142 enrolled
Drug / intervention
Preoperative radiotherapyradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01216189
NCT01216189N/ACompleted
CompareCT.gov

Sexual Function and Wellbeing in Females Diagnosed With Rectal Cancer

Karolinska Institutet·observational·Posted Oct 7, 2010·Updated Apr 9, 2021

In Brief

An observational study evaluating Preoperative radiotherapy for Rectal Cancer. Completed, enrolled 142 participants across 5 sites.

Detailed Summary

Preoperative radiotherapy (RT) and pelvic surgery is recommended to many patients with rectal cancer. For women there are theoretical reasons to believe that the treatment may affect hormone levels, sexual function and wellbeing. To address these questions a longitudinal observational study was initiated where androgen levels and sexual function were assessed before treatment (baseline) and during a follow-up period of two years.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsRectal Cancer
CountriesSweden
CollaboratorsSwedish Cancer Society

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 7, 2010
Enrollment StartJun 1, 2008
Primary CompletionDec 1, 2013
Study CompletionDec 1, 2015
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 15.7 years ago

Interventions

Preoperative radiotherapyradiation

Preoperative radiotherapy (RT) was administered as either short course (5Gy x5) or long-course (2Gy x25 or 1.8 Gy x25 with or without 3 fractions of boost to the primary tumor and radiologically malignant lymph nodes) treatment with or without concomitant or sequential chemotherapy. Oncological treatment was decided at a multidisciplinary team conference.