CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 306 enrolled
Drug / intervention
Metoclopramide +2 moredrug
Likely dose
Metoclopramide 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01216410
NCT01216410N/ACompleted

The Effect of Adding Metoclopramide and Ondansetron to a Prophylactic Phenylephrine Infusion for the Management of Nausea and Vomiting Associated With Spinal Anesthesia for Cesarean Section

Duke University·interventional·Posted Oct 7, 2010·Updated Aug 6, 2014

In Brief

A clinical study evaluating Metoclopramide, Phenylephrine infusion, and 1 other intervention for Cesarean Delivery. Completed, enrolled 306 participants across 1 site.

Detailed Summary

The study investigates the incidence of intraoperative nausea and vomiting under spinal anesthesia using a phenylephrine infusion with and without prophylactic antiemetics.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsIWK Health Centre

Timeline

N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedOct 7, 2010
Enrollment StartDec 1, 2008
Primary CompletionApr 1, 2011
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 15.7 years ago

Interventions

Metoclopramidedrug

Prophylactic Metoclopramide 10 mg given before spinal together with prophylactic phenylephrine infusion

Phenylephrine infusiondrug

Prophylactic phenylephrine infusion after spinal and placebo antiemetics

Combination Groupdrug

Metoclopramide and ondansetron prophylaxis with phenylephrine infusion