At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase III Surgical Trial to Evaluate the Benefit of a Standard Versus an Extended Pelvic Lymphadenectomy Performed at Time of Radical Cystectomy for Muscle Invasive Urothelial Cancer
In Brief
A clinical study evaluating therapeutic conventional surgery, therapeutic standard lymphadenectomy, and 1 other intervention for Bladder Cancer. Completed, enrolled 658 participants across 35 sites in 2 countries.
Detailed Summary
RATIONALE: Lymphadenectomy may remove tumor cells that have spread to nearby lymph nodes in patients with invasive bladder cancer. It is not yet known whether extended pelvic lymphadenectomy is more effective than standard pelvic lymphadenectomy during surgery. PURPOSE: This randomized phase II trial is studying standard pelvic lymphadenectomy to see how well it works compared to extended pelvic lymphadenectomy in treating patients undergoing surgery for invasive bladder cancer.
Study Details
Timeline
Interventions
Patients undergo radical cystectomy
Patients undergo standard pelvic lymphadenectomy.
Patients undergo extended pelvic lymphadenectomy