CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 89 enrolled
Drug / intervention
Simvastatin +2 moredrug
Likely dose
Simvastatin 20 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01225263
NCT01225263Phase 2Completed

Combined Statin and Vitamin D Therapy for Prophylactic Treatment of Episodic Migraine

Rami Burstein·interventional·Posted Oct 20, 2010·Updated Jan 26, 2016

In Brief

A Phase 2 clinical trial evaluating Simvastatin, Vitamin D, and 1 other intervention for Migraine. Completed, enrolled 89 participants across 1 site.

Detailed Summary

The investigators are studying if taking simvastatin and vitamin D together will help prevent episodic migraines. Simvastatin is an FDA approved drug that is typically used to treat high cholesterol and reduce the risk of stroke and heart attack. Vitamin D is a vitamin found in certain foods like some types of fish, and in nutritional supplements. This study is 9 months long. Some people who participate will receive simvastatin and vitamin D, and some people will receive a placebo. A placebo is a "sugar pill" that looks like medication but does not have any active ingredients in it. The investigators hypothesize that taking vitamin D and simvastatin daily may reduce the number of migraines people who have episodic migraine get.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMigraine
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedOct 20, 2010
Enrollment StartSep 1, 2010
Primary CompletionJan 1, 2015
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 15.7 years ago

Interventions

Simvastatindrug

simvastatin, 20 mg, twice daily for 6 months

Vitamin Ddietary

Vitamin D3, 1000 IU, twice daily for 6 months

Placeboother

Two placebo pills, taken twice daily for 6 months