At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 21,379 enrolled
Drug / intervention
Ticagrelor 90 mg +2 moredrug
Likely dose
Ticagrelor 90 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multinational Trial, to Assess the Prevention of Thrombotic Events With Ticagrelor Compared to Placebo on a Background of Acetyl Salicylic Acid (ASA) Therapy in Patients With History of Myocardial Infarction
In Brief
A Phase 3 clinical trial evaluating Ticagrelor 90 mg, Ticagrelor 60 mg, and 1 other intervention for Myocardial Infarction and 3 related conditions. Completed, enrolled 21,379 participants across 826 sites in 31 countries.
Detailed Summary
This study is being carried out to see if a new drug called ticagrelor given twice daily in addition to the ASA therapy decreases the frequency of cardiovascular events (e.g., death from heart disease, heart attack, or stroke).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMyocardial Infarction, Cardiovascular Death, Atherothrombosis, Stroke
CountriesArgentina, Australia, Belgium, Brazil, Bulgaria, Canada, Chile, China, Colombia, Czechia, France, Germany, Hungary, Italy, Japan, Netherlands, Norway, Peru, Philippines, Poland, Romania, Russia, Slovakia, South Africa, South Korea, Spain, Sweden, Turkey (Türkiye), Ukraine, United Kingdom, United States
Collaborators--
Timeline
Phase 3CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
Enrollment StartOct 2010
First PostedOct 2010
Primary CompletionDec 2014
TodayJul 2026
First PostedOct 21, 2010
Enrollment StartOct 1, 2010
Primary CompletionDec 1, 2014
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 15.7 years ago
Interventions
Ticagrelor 90 mgdrug
Oral dose twice a day
Ticagrelor 60 mgdrug
Oral dose twice a day
Ticagrelor Placebodrug
Oral dose twice a day