At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 107 enrolled
Drug / intervention
Transfusion of blood productsbiological
Likely dose
Transfusion of blood products 1 unitfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Early Whole Blood in Patients Requiring Transfusion After Major Trauma
The University of Texas Health Science Center, Houston·interventional·Posted Oct 22, 2010·Updated Jun 4, 2018
In Brief
A Phase 4 clinical trial evaluating Transfusion of blood products for Trauma/Injury Problem. Completed, enrolled 107 participants across 1 site.
Detailed Summary
The proposal will assess if patients who require massive transfusion can be accurately predicted early after emergency department arrival and assess if the use of stored whole blood during initial resuscitation will reduce transfusion needs compared to transfusion with component therapy and thus improve outcome.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTrauma/Injury Problem
CountriesUnited States
CollaboratorsU.S. Army Medical Research and Development Command
Timeline
Phase 4CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedOct 2010
Enrollment StartMay 2011
Primary CompletionAug 2012
Study CompletionDec 2012
TodayJul 2026
First PostedOct 22, 2010
Enrollment StartMay 1, 2011
Primary CompletionAug 1, 2012
Study CompletionDec 1, 2012
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 15.7 years ago
Interventions
Transfusion of blood productsbiological
The intervention will be either a) administration of 1 unit of whole blood plus pooled products or b) administration of component therapy (red blood cells, plasma, platelets).