At a glance
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A Randomized, Double-Blind, Placebo Controlled Study of Nitazoxanide in Adults and Adolescents With Acute Uncomplicated Influenza
In Brief
A Phase 3 clinical trial evaluating Nitazoxanide and Placebo for Influenza. Completed, enrolled 624 participants across 1 site.
Detailed Summary
This is a randomized clinical trial designed to evaluate the safety/efficacy of two dosing regimens of oral nitazoxanide compared to placebo in the treatment of acute uncomplicated influenza in adults and adolescents. The investigators hypothesize that treatment with Nitazoxanide will reduce the duration of symptoms in patients with confirmed influenza infection. Secondarily, the investigators hypothesize that treatment with nitazoxanide will reduce the complications of influenza, severity of symptoms, time lost from work, time to return to normal daily activities.
Study Details
Timeline
Interventions
Tablets, 300 mg (one 300 mg tablet + 1 placebo tablet) with food twice daily for 5 days
Tablets, 600 mg (two 300 mg tablets) with food twice daily for 5 days
Tablets, (2 tablets) twice daily with food for 5 days