At a glance
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A Prospective Evaluation of Thromboelastography for Identifying Coagulopathy in Severely Injured Patients
In Brief
An observational study evaluating RapidTEG test for Coagulopathy. Completed, enrolled 1,450 participants across 3 sites.
Detailed Summary
The purpose of this study is to evaluate the clinical utility of thrombelastography (TEG) to predict and identify trauma patients at increased risk of receiving blood transfusion, develop multiple organ failure and mortality. TEG has been proposed as a superior tool to rapidly diagnose and help guide resuscitation with blood products and preclinical data suggest that TEG is both more sensitive and specific than PT or PTT for coagulation abnormalities. Based on the preclinical work led by Dr. Holcomb, our hypothesis is that the Rapid TEG will help to identify these coagulopathic patients earlier, allow for rapid MT protocol activation, and assist in developing data driven blood product transfusion guidelines.
Study Details
Timeline
Interventions
The RapidTEG test will be done at the study time points (3, 6, 12, 24 hours and 4 addiitonal days).