CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 25 enrolled
Drug / intervention
Atazanavir +9 moredrug
Likely dose
Atazanavir 300 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01232127
NCT01232127Phase 4Completed

Open-Label, Multiple-Dose, Drug Interaction Study to Assess the Effect of Famotidine on the Pharmacokinetics of Atazanavir in HIV-Infected Subjects Receiving Atazanavir With Ritonavir and Tenofovir

Bristol-Myers Squibb·interventional·Posted Nov 2, 2010·Updated Aug 31, 2012

In Brief

A Phase 4 clinical trial evaluating Atazanavir, Ritonavir, and 3 other interventions for HIV. Completed, enrolled 25 participants across 2 sites in 2 countries.

Detailed Summary

The purpose of this study is to assess the effects of famotidine, given twice daily, on atazanavir administered with ritonavir and tenofovir in HIV-infected participants.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV
CountriesGermany, United Kingdom
Collaborators--

Timeline

Phase 4CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedNov 2, 2010
Enrollment StartFeb 1, 2011
Primary CompletionJun 1, 2011
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 15.7 years ago

Interventions

Atazanavirdrug

Capsule, oral, 300 mg, once daily, 10 days

Atazanavirdrug

Capsule, oral, 400 mg, once daily, 7 days

Ritonavirdrug

Capsule, oral, 100 mg, once daily, 10 days

Ritonavirdrug

Capsule, oral, 100 mg, once daily, 7 days

Tenofovir (TDF)drug

Capsule, oral, 300 mg, once daily, 10 days

Tenofovir (TDF)drug

Capsule, oral, 300 mg, once daily, 7 days

Nucleoside Reverse Transcriptase Inhibitor (NRTI)drug

Oral, 10 days

Nucleoside Reverse Transcriptase Inhibitor (NRTI)drug

Oral, 7 days

Famotidine (FAM)drug

Tablet, oral, 20 mg, twice daily, 7 days

Famotidine (FAM)drug

Tablet, oral, 40 mg, twice daily, 7 days