CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 25 enrolled
Drug / intervention
1% Lidocaine with Epinephrine (1:100,000) +3 moredrug
Likely dose
1% Lidocaine with Epinephrine (1:100,000) 0.2mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01243112
NCT01243112Phase 4Completed
CompareCT.gov

Onset and Duration of Effect of Lidocaine, Bupivacaine, and Lidocaine/Bupivacaine Mixture With Epinephrine.

Scott and White Hospital & Clinic·interventional·Posted Nov 18, 2010·Updated Dec 2, 2011

In Brief

A Phase 4 clinical trial evaluating 1% Lidocaine with Epinephrine (1:100,000), 0.25% Bupivacaine with Epinephrine (1:200,000), and 2 other interventions for Pain. Completed, enrolled 25 participants across 1 site.

Detailed Summary

Purpose and Background The purpose of this research study is to investigate the benefits of mixing lidocaine and bupivacaine for numbing the skin. Lidocaine and bupivacaine are two commonly used medications to numb the skin for minor procedures. Lidocaine has a faster onset. Bupivacaine has a longer duration. They are often combined with epinephrine to increase the length of action. These medications are used to control pain at the time of the operation and to decrease discomfort immediately afterward. Participating in the study involves injection of local anesthetic containing lidocaine, bupivacaine, and lidocaine and bupivacain with epinephrine at 4 sites on the forearm. Your participation will potentially improve the administration of these medications in persons undergoing a variety of procedures. You will be one of approximately 25 healthy volunteer subjects in this research study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedNov 18, 2010
Enrollment StartMay 1, 2010
Primary CompletionSep 1, 2010
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 15.6 years ago

Interventions

1% Lidocaine with Epinephrine (1:100,000)drug

0.2ml Intradermal injection once.

0.25% Bupivacaine with Epinephrine (1:200,000)drug

0.2ml Intradermal injection once.

0.5% Lidocaine, 0.125 Bupivacaine, and epi (1:150,000)drug

0.2ml Intradermal injection once.

1% Lidocaine, 0.5% Bupivacaine, and epinephrine (1:150,000)drug

0.2ml Intradermal injection once.