At a glance
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Study of Maternal-foetal Cytomegalovirus (CMV) Transmission
In Brief
A clinical study evaluating Blood sample, Cord blood sample, and 3 other interventions for Infections, Cytomegalovirus and Cytomegalovirus Infections. Completed, enrolled 160 participants across 9 sites.
Detailed Summary
This study is designed to evaluate maternal virological and immunological parameters to determine their ability to predict congenital cytomegalovirus (CMV) infection. When a pregnant woman is infected with CMV, her immune system (which protects her from infection) is activated and the virus can be found in the woman's bodily fluids (blood, saliva, urine, vaginal secretions). The aim of this study is to find out if there is a link between either the pregnant woman's immune response or the presence of the virus in these bodily fluids and the child/foetus being infected with the virus.
Study Details
Timeline
Interventions
Blood sample at study entry, every two months during pregnancy, at pregnancy conclusion and one month after pregnancy conclusion.
Cord blood sample taken at the time of delivery.
Saliva swab taken at study entry, every month during pregnancy, at pregnancy conclusion and one month after pregnancy conclusion.
Approximately 10 mL of urine will be sampled at study entry, every month during pregnancy, at pregnancy conclusion and one month after pregnancy conclusion.
Vaginal swab taken at study entry, every month during pregnancy and one month after pregnancy conclusion.