CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 74 enrolled
Drug / intervention
Amoxicillin +1 moredrug
Likely dose
Amoxicillin 30mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01253980
NCT01253980N/ACompleted
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The Efficacy of Prophylactic Antibiotics in the Management of Pneumonitis Following Paraffin (Kerosene) Ingestion in Children

University of Cape Town·interventional·Posted Dec 6, 2010·Updated Nov 9, 2015

In Brief

A clinical study evaluating Amoxicillin and Placebo for Kerosene Pneumonitis. Completed, enrolled 74 participants across 1 site.

Detailed Summary

Paraffin (kerosene) ingestion in the developing world accounts for a large number of visits to healthcare facilities, especially amongst children. There is no evidence in animals and no good evidence in humans that the use of early antibiotics improves the clinical outcome of paraffin-induced pneumonitis. This randomised placebo-controlled trial will investigate whether the use of early antibiotics affects the clinical course of children with pneumonitis following paraffin ingestion.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKerosene Pneumonitis
CountriesSouth Africa
Collaborators--

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedDec 6, 2010
Enrollment StartJul 1, 2010
Primary CompletionSep 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 15.6 years ago

Interventions

Amoxicillindrug

Amoxicillin syrup 20-30mg/kg 8 hourly for 5 days

Placebodrug

Placebo suspension made of water, dextrose and glycerine with a similar taste and appearance to the active comparator. Dose 20-30mg/kg 8 hourly for 5 days