CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 250 enrolled
Drug / intervention
Live, attenuated, recombinant dengue serotypes 1, 2, 3, and 4 virus +1 morebiological
Likely dose
Live, attenuated, recombinant dengue serotypes 1, 2, 3, and 4 virus 0.5 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01254422
NCT01254422Phase 3Completed

Safety and Immunogenicity of a Tetravalent Dengue Vaccine in Healthy Children Aged 2 to 11 Years in Malaysia

Sanofi·interventional·Posted Dec 6, 2010·Updated Mar 25, 2022

In Brief

A Phase 3 clinical trial evaluating Live, attenuated, recombinant dengue serotypes 1, 2, 3, and 4 virus and Placebo: NaCl 0.9% for Dengue Fever and Dengue Hemorrhagic Fever. Completed, enrolled 250 participants across 4 sites.

Detailed Summary

The purpose of this study was to evaluate the safety and immunogenicity of Phase III lots of the CYD dengue vaccine in a pediatric population in Malaysia. Primary Objectives: * To describe the safety (in terms of solicited and unsolicited adverse events) of the CYD dengue vaccine in all participants after each injection. * To describe the antibody response to each dengue virus serotype post-injection 2 and post-injection 3.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesMalaysia
Collaborators--

Timeline

Phase 3CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedDec 6, 2010
Enrollment StartDec 2, 2010
Primary CompletionSep 28, 2012
Study CompletionJan 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 15.6 years ago

Interventions

Live, attenuated, recombinant dengue serotypes 1, 2, 3, and 4 virusbiological

0.5 mL (at 0, 6, and 12 months), Subcutaneous suspension

Placebo: NaCl 0.9%biological

0.5 mL (at 0, 6, and 12 months), Subcutaneous suspension