CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
Local medical treatment of raised intraocular pressure +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01255306
NCT01255306N/ACompleted
CompareCT.gov

The Influence of Silicone Oil on Nerve Fiber Layer Thickness After Pars Plana Vitrectomy

University Hospital Sestre Milosrdnice·observational·Posted Dec 7, 2010·Updated Mar 23, 2012

In Brief

An observational study evaluating Optical coherence tomography and Local medical treatment of raised intraocular pressure for Rhegmatogenous Retinal Detachment and 2 related conditions. Completed, enrolled 60 participants across 1 site.

Detailed Summary

The aim of the study is to evaluate the influence of silicone oil on thickness of the retinal nerve fiber layer by using optical coherence tomography (OCT) in patients following pars plana vitrectomy.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsRhegmatogenous Retinal Detachment, Toxic Effect of Silicone, Glaucoma Due to Silicon Oil
CountriesCroatia
Collaborators--

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedDec 7, 2010
Enrollment StartApr 1, 2010
Primary CompletionNov 1, 2011
Study CompletionDec 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 15.6 years ago

Interventions

Optical coherence tomographyother

Optical coherence tomography will be performed in all study patients following pars plans vitrectomy and silicone oil tamponade. A fellow eye of each patient will serve as a control. Each patient enrolled in a study will receive 4 measurements: 1. On 7th postoperative day 2. On 30th postoperative day 3. On 90th postoperative day 4. On 180th postoperative day

Local medical treatment of raised intraocular pressuredrug

In patients with raised intraocular pressure following medications will be employed in order to control the intraocular pressure: Cosopt (dorzolamide hydrochloride-timolol maleate ophthalmic solution; b.i.d.) Ganfort (Bimatoprost, timolol maleate ophthalmic solution; once daily) Alphagan (Brimonidine ophthalmic solution; b.i.d.) In patients with intraocular pressure less than 27 mmHg Alphagan will be prescribed. In patients with intraocular pressure greater than 27 mmHg either Cosopt, or Ganfort will be prescribed under the discretion of treating physician. If intraocular pressure in patients treated with either Cosopt or Ganfort does not drop under 21 mmHg, Alphagan will be added.