CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 16 enrolled
Drug / intervention
MK-8266 +1 moredrug
Likely dose
MK-8266 0.1 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01263314
NCT01263314Phase 1Completed

A Single Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of MK-8266 in Elderly Subjects With Hypertension

Merck Sharp & Dohme LLC·interventional·Posted Dec 20, 2010·Updated Nov 5, 2018

In Brief

A Phase 1 clinical trial evaluating MK-8266 and Placebo for Hypertension. Completed, enrolled 16 participants.

Detailed Summary

This is a randomized, double-blind, placebo-controlled study. The hypothesis for this study is that single oral doses of MK-8266 selected for this study are sufficiently safe and well tolerated by elderly male and elderly female participants with hypertension to permit continued clinical investigation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypertension
Countries--
Collaborators--

Timeline

Phase 1CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedDec 20, 2010
Enrollment StartNov 1, 2010
Primary CompletionFeb 1, 2011
Study CompletionMar 1, 2011
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 15.5 years ago

Interventions

MK-8266drug

Oral capsules, 0.1 mg potency

Placebodrug

Oral placebo capsules to match MK-8266 capsules