CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 7 enrolled
Drug / intervention
Injectable clostridial collagenasebiological
Likely dose
Injectable clostridial collagenase 0.58mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01265420
NCT01265420Phase 4Completed
CompareCT.gov

The Efficacy and Safety of Xiaflex Injections for the Treatment of Thumb Cords in Dupuytren's Contractures

Indiana Hand to Shoulder Center·interventional·Posted Dec 23, 2010·Updated Apr 30, 2015

In Brief

A Phase 4 clinical trial evaluating Injectable clostridial collagenase for Dupuytren's Contracture. Completed, enrolled 7 participants across 1 site.

Detailed Summary

This study will evaluate the efficacy and safety of clostridial collagenase injections for treatment of Dupuytren's contracture of the thumb and first web space. The investigators hypothesis is that clostridial collagenase will have safety not significantly different to that demonstrated in Phase III clinical trials, and will be effective in significantly reducing the degree of thumb contracture.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDupuytren's Contracture
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedDec 23, 2010
Enrollment StartDec 1, 2010
Primary CompletionFeb 1, 2014
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 15.5 years ago

Interventions

Injectable clostridial collagenasebiological

Injection of 0.58mg clostridial collagenase into Dupuytren's cord, up to three injections