At a glance
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Randomized Trial of Hypofractionated Whole Breast Irradiation Versus Conventionally Fractionated Whole Breast Irradiation for Ductal Carcinoma In Situ and Early Invasive Breast Cancer
In Brief
A Phase 2 clinical trial evaluating External Beam Radiation Therapy, Hypofractionated Radiation Therapy, and 4 other interventions for Ductal Breast Carcinoma In Situ and 7 related conditions. Active but no longer recruiting, targeting 301 participants across 7 sites.
Detailed Summary
This randomized phase II trial studies how well hypofractionated radiation therapy (RT) works compared to standard RT in treating patients with ductal breast carcinoma in situ (DCIS) or early invasive breast cancer. Radiation therapy (RT) uses high energy x-rays to kill tumor cells. Giving higher doses of RT over a shorter period of time may kill more tumor cells and have fewer side effects. It is not yet known if hypofractionated RT is more effective than standard RT in treating breast cancer.
Study Details
Timeline
Interventions
Undergo HF-WBI
Undergo CF-WBI
Undergo HF-WBI
Optional correlative studies
Ancillary studies
Ancillary studies
Undergo HF-WBI
Undergo CF-WBI