CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 22 enrolled
Drug / intervention
Repetitive transorbital alternating current stimulationdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01270126
NCT01270126N/ACompleted
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Treatment of Patients With Optic Neuropathy Using Transorbital Alternating Current Stimulation - a Randomized Trial

University of Magdeburg·interventional·Posted Jan 5, 2011·Updated Nov 9, 2020

In Brief

A clinical study evaluating Repetitive transorbital alternating current stimulation for Optic Nerve Diseases and 2 related conditions. Completed, enrolled 22 participants across 1 site.

Detailed Summary

Non-invasive brain stimulation can increase cortical excitability in the visual system, but it is not known if this is of clinical value. The investigators now assessed if repetitive, transcranial alternating current stimulation (rtACS) can improve visual field size in patients with optic nerve damage. The investigators hypothesized that rtACS would improve visual functions within the defective visual field sectors of the visual field (primary outcome measure).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOptic Nerve Diseases, Optic Nerve Injuries, Optic Neuropathies
CountriesGermany
CollaboratorsEBS Technologies GmbH

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 5, 2011
Enrollment StartNov 1, 2006
Primary CompletionDec 1, 2010
TodayJul 2, 2026
Enrollment to primary: 4.1 yearsPosted 15.5 years ago

Interventions

Repetitive transorbital alternating current stimulationdevice

Repetitive, transorbital alternating current stimulation (rtACS) was applied with a multi-channel device generating weak current pulses in predetermined firing bursts of 2 to 9 pulses. The amplitude of each current pulse was below 1000µA. Current intensity was individually adjusted according to how well patients perceived phosphenes, i.e. any sensation of flickering light in response to the rtACS stimulation.