CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 18 enrolled
Drug / intervention
Hsp90 inhibitor STA-9090 +7 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01270880
NCT01270880Phase 2Completed
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A Phase II Trial of STA-9090 in Patients With Metastatic Castration-Resistant Prostate Cancer (CRPC) Pretreated With Docetaxel Based Chemotherapy

Barbara Ann Karmanos Cancer Institute·interventional·Posted Jan 5, 2011·Updated Sep 18, 2018

In Brief

A Phase 2 clinical trial evaluating Hsp90 inhibitor STA-9090, laboratory biomarker analysis, and 6 other interventions for Adenocarcinoma of the Prostate and 3 related conditions. Completed, enrolled 18 participants across 4 sites.

Detailed Summary

Hsp90 inhibitor STA-9090 may stop the growth of tumor cells by blocking some of the proteins needed for cell growth. This phase II trial is studying how well Hsp90 inhibitor STA-9090 works in treating patients with metastatic hormone-resistant prostate cancer previously treated with docetaxel-based chemotherapy

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAdenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer, Stage IV Prostate Cancer
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

Phase 2CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJan 5, 2011
Enrollment StartJan 1, 2011
Primary CompletionJul 1, 2014
TodayJul 2, 2026
Enrollment to primary: 3.5 yearsPosted 15.5 years ago

Interventions

Hsp90 inhibitor STA-9090drug

Given IV

laboratory biomarker analysisother

Correlative studies

polymerase chain reactiongenetic

Correlative studies

enzyme-linked immunosorbent assayother

Correlative studies

RNA analysisgenetic

Correlative studies

spectrophotometryother

Correlative studies

reverse transcriptase-polymerase chain reactiongenetic

Correlative studies

gene expression analysisgenetic

Correlative studies