CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 259 enrolled
Drug / intervention
AC-201, 25mg +3 moredrug
Likely dose
AC-201, 25mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01276106
NCT01276106Phase 2Completed

A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Phase II Study of AC-201 in Patients With Type 2 Diabetes Mellitus

TWi Biotechnology, Inc.·interventional·Posted Jan 13, 2011·Updated May 22, 2018

In Brief

A Phase 2 clinical trial evaluating AC-201, 25mg, AC-201, 50mg, and 2 other interventions for Type 2 Diabetes Mellitus. Completed, enrolled 259 participants across 21 sites in 2 countries.

Detailed Summary

This is a 24-week randomized placebo-controlled study to investigate the effect of an oral IL-1beta inhibitor AC-201 in patients with type 2 diabetes mellitus already treated on different background diabetes therapies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTaiwan, United States
Collaborators--

Timeline

Phase 2CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJan 13, 2011
Enrollment StartJan 1, 2011
Primary CompletionFeb 1, 2012
Study CompletionMar 1, 2012
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 15.5 years ago

Interventions

AC-201, 25mgdrug

Capsule, 25mg BID

AC-201, 50mgdrug

Capsule, 50mg BID

AC-201, 75mgdrug

Capsule, 75mg BID

Placebodrug

Placebo BID