CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 727 enrolled
Drug / intervention
Fluticasone furoate 27.5 mcg/actuation nasal spray (Lek Pharmaceuticals) +2 moredrug
Likely dose
Fluticasone furoate 27.5 mcg/actuation nasal spray (Lek Pharmaceuticals)from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01279057
NCT01279057Phase 3Completed

A Double-Blind, Randomized, Placebo Controlled, Parallel Group, Multi-Site Study to Compare the Clinical Equivalence of Fluticasone Furoate Nasal Spray (Lek Pharmaceuticals) With Veramyst® Nasal Spray (GlaxoSmithKline) in the Relief of the Signs and Symptoms of Seasonal Allergic Rhinitis

Sandoz·interventional·Posted Jan 19, 2011·Updated Feb 3, 2021

In Brief

A Phase 3 clinical trial evaluating Fluticasone furoate 27.5 mcg/actuation nasal spray (Lek Pharmaceuticals), Fluticasone furoate (Veramyst®) 27.5 mcg/actuation nasal spray, and 1 other intervention for Rhinitis, Allergic, Seasonal. Completed, enrolled 727 participants across 7 sites.

Detailed Summary

This study compared the safety and efficacy of a generic fluticasone furoate (Lek Pharmaceuticals) nasal spray to the reference listed drug in the treatment of seasonal allergic rhinitis. Additionally both the test and the reference formulations were tested for superiority against a placebo nasal spray.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJan 19, 2011
Enrollment StartDec 27, 2010
Primary CompletionFeb 8, 2011
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 15.5 years ago

Interventions

Fluticasone furoate 27.5 mcg/actuation nasal spray (Lek Pharmaceuticals)drug

Nasal spray administered once daily at a dose of 110 mcg (4 actuations) for 14 days.

Fluticasone furoate (Veramyst®) 27.5 mcg/actuation nasal spraydrug

Nasal spray administered once daily at a dose of 110 mcg (4 actuations) for 14 days.

Placebodrug

Placebo nasal spray administered once daily (4 actuations) for 14 days.