CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 145 enrolled
Drug / intervention
Darunavir +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01281813
NCT01281813Phase 3Completed

Continued Access to Darunavir/Ritonavir (DRV/Rtv) in HIV-1 Infected Adults, Adolescents and Children Aged 3 Years and Above

Janssen Sciences Ireland UC·interventional·Posted Jan 24, 2011·Updated Oct 31, 2022

In Brief

A Phase 3 clinical trial evaluating Darunavir and Ritonavir for HIV-1 Infections. Completed, enrolled 145 participants across 17 sites in 8 countries.

Detailed Summary

The primary objective of this trial is to continue the provision of darunavir/ low-dose ritonavir (DRV/rtv) to adult and pediatric patients who previously received DRV/rtv in the clinical trials TMC114-C211, TMC114-C214, TMC114-TiDP31-C229 or in the pediatric trial TMC114-TiDP29-C232 who continue to benefit from the use of darunavir in combination with low-dose ritonavir (DRV/rtv), in countries where DRV is not commercially available for the subject, is not reimbursed, or cannot be accessed through another source (e.g., access program, governmental program) and to provide DRV through this trial until the participants can switched to locally available DRV-based treatment regimens (that is commercially available and reimbursed, or accessible through another source \[for example, access program or government program\]) or to local standard of care, as appropriate.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBrazil, Costa Rica, Guatemala, Malaysia, Panama, South Africa, Thailand, Ukraine
Collaborators--

Timeline

Phase 3CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJan 24, 2011
Enrollment StartAug 8, 2011
Primary CompletionJul 29, 2021
TodayJul 2, 2026
Enrollment to primary: 10.0 yearsPosted 15.4 years ago

Interventions

Darunavirdrug

Participants will receive darunavir (per parent study) as oral suspension.

Ritonavirdrug

Participants will receive ritonavir (per parent study) as oral solution/suspension.