CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 20 enrolled
Drug / intervention
Antiretroviral therapy (ART) +2 moredrug
Likely dose
raltegravir 400 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01285050
NCT01285050Phase 4Completed
CompareCT.gov

Interferon Alfa Sensitivity in HIV/HCV Coinfected Persons Before and After Antiretroviral Therapy

Johns Hopkins University·interventional·Posted Jan 27, 2011·Updated Nov 29, 2016

In Brief

A Phase 4 clinical trial evaluating Antiretroviral therapy (ART), raltegravir, and 1 other intervention for HIV Infection and Hepatitis C. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The chief purpose of this research is to evaluate interferon alpha sensitivity and cell type specific levels of interferon receptor and interferon stimulated genes and proteins in HIV/ HCV (hepatitis C virus) coinfected persons before and after administration of HIV medications (antiretroviral therapy).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV Infection, Hepatitis C
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)

Timeline

Phase 4CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJan 27, 2011
Enrollment StartJan 1, 2011
Primary CompletionApr 1, 2015
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 15.4 years ago

Interventions

Antiretroviral therapy (ART)drug

Peginterferon alfa-2b administered once as part of a pharmacokinetic study before and after anti-HIV medications. Peginterferon is used to produce a measurement but the intervention is the HIV medications which are specified as raltegravir, emtricitabline, and tenofovir disoproxil fumerate.

raltegravirdrug

raltegravir is an HIV medication given 400 mg twice daily by mouth

Emtricitabine and tenofovir disoproxil fumaratedrug

Emtricitabine and tenofovir disoproxil fumarate are HIV medications, combination pill, once per day by mouth