At a glance
ClinicalIndex Comparison RecordN/ACompleted· 45 enrolled
Drug / intervention
Nasal allergen challengeprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparative Responses to Nasal Allergen Challenge in Allergic Rhinitic Subjects With or Without Asthma
In Brief
A clinical study evaluating Nasal allergen challenge for Asthma and Allergic Rhinitis. Completed, enrolled 45 participants across 1 site.
Detailed Summary
Background: Nasal allergen challenge (NAC) is useful to study the pathophysiology of rhinitis, and multiple challenges may more adequately approximate natural exposure. Objective: To determine the effect of 4 consecutive daily NAC, on clinical and inflammatory parameters in rhinitics with or without asthma.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma, Allergic Rhinitis
CountriesCanada
CollaboratorsAllerGen NCE Inc.
Timeline
N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartNov 2005
Primary CompletionMar 2008
First PostedJan 2011
TodayJul 2026
First PostedJan 31, 2011
Enrollment StartNov 1, 2005
Primary CompletionMar 1, 2008
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 15.4 years ago
Interventions
Nasal allergen challengeprocedure
Allergen sprayed into nostrils. Allergen used will be house dust mite or cat allergen. Allergens will be given in increasing ten-fold dilutions until a positive response occurs.