CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 28 enrolled
Drug / intervention
Pentoxifylline +1 moredrug
Likely dose
Pentoxifylline 400 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01292005
NCT01292005Early Ph 1Completed

Pentoxifylline Treatment in Acute Pancreatitis; A Double-Blind Placebo-Controlled Randomized Trial

Mayo Clinic·interventional·Posted Feb 9, 2011·Updated Oct 25, 2016

In Brief

A Early Phase 1 clinical trial evaluating Pentoxifylline and Placebo for Acute Pancreatitis. Completed, enrolled 28 participants across 1 site.

Detailed Summary

The purpose of this study is to determine the effects (good and bad) of giving a drug called pentoxifylline to patients with acute pancreatitis, to see if it can improve blood tests associated with inflammation (tissue damage). Pentoxifylline is approved by the US Food and Drug Administration (FDA) for treatment of circulation problems, but its use in this study is investigational, which means that the FDA has not approved it for the treatment of pancreatitis. However, the FDA has allowed the use of pentoxifylline in this research study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Early Ph 1CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedFeb 9, 2011
Enrollment StartApr 1, 2009
Primary CompletionJul 1, 2012
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 15.4 years ago

Interventions

Pentoxifyllinedrug

400 mg, 3 times daily by mouth from time of enrollment until 72 hours from enrollment. Subjects received up to a maximum of 9 doses.

Placebodrug

400 mg, 3 times daily by mouth from time of enrollment until 72 hours from enrollment. Subjects received up to a maximum of 9 doses.