At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 51 enrolled
Drug / intervention
Mifepristone +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Evaluation of Cortisol Resistance in Young Sedentary and Endurance-trained Men and Elderly Sedentary Men
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)·interventional·Posted Feb 11, 2011·Updated Jul 15, 2024
In Brief
A Phase 2 clinical trial evaluating Mifepristone, Placebo, and 3 other interventions for Cortisol Resistance and 4 related conditions. Completed, enrolled 51 participants across 1 site.
Detailed Summary
This study proposes to examine multiple aspects of the hypothalamic-pituitary-adrenal axis in younger endurance trained and sedentary men, and in older sedentary men.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCortisol Resistance, Negative Feedback, ACTH, Mineralcorticoid, Glucocorticoid
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
Enrollment StartJan 2011
First PostedFeb 2011
Primary CompletionAug 2016
TodayJul 2026
First PostedFeb 11, 2011
Enrollment StartJan 24, 2011
Primary CompletionAug 10, 2016
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 15.4 years ago
Interventions
Mifepristonedrug
Placebodrug
Spironolactonedrug
Combineddrug
Dexamethasonedrug