CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 94 enrolled
Drug / intervention
Exenatide +2 moredrug
Likely dose
Moxifloxacin 400 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01297062
NCT01297062Phase 1Completed

A Randomized, Phase 1, Three-Period, Placebo- and Positive-Controlled, Double-Blind, Crossover Study to Assess the Electrophysiological Effects of Exenatide at Therapeutic and Supratherapeutic Concentrations on the 12-Lead Electrocardiogram QT Interval in Healthy Subjects

AstraZeneca·interventional·Posted Feb 16, 2011·Updated Apr 14, 2015

In Brief

A Phase 1 clinical trial evaluating Exenatide, Moxifloxacin, and 1 other intervention for Healthy Subjects. Completed, enrolled 94 participants across 2 sites.

Detailed Summary

Compare the effect of exenatide (therapeutic and supratherapeutic concentrations), moxifloxacin and placebo on the QT interval.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 1CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedFeb 16, 2011
Enrollment StartFeb 1, 2011
Primary CompletionApr 1, 2011
Study CompletionMay 1, 2011
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 15.4 years ago

Interventions

Exenatidedrug

IV Exenatide (therapeutic and supratherapeutic concentrations)

Moxifloxacindrug

Oral Moxifloxacin (400 mg)

Placebo comparatordrug

IV Placebo (matching volume of placebo)