CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 400 enrolled
Drug / intervention
Loop Electrosurgical Excision Procedure (LEEP) +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01298596
NCT01298596N/ACompleted
CompareCT.gov

Impact of Cryotherapy Versus Loop Electrosurgical Excision Procedure (LEEP) on Recurrence of Cervical Intraepithelial Neoplasia and HIV-1 Cervical Shedding Among HIV-positive Women

University of Washington·interventional·Posted Feb 17, 2011·Updated Nov 12, 2019

In Brief

A clinical study evaluating Loop Electrosurgical Excision Procedure (LEEP) and Cryotherapy for Cervical Intraepithelial Neoplasia. Completed, enrolled 400 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the rate of recurrence of cervical intraepithelial neoplasia among HIV-positive women receiving cryotherapy versus LEEP over 2 years of follow-up and to compare the shedding of HIV-1 from the cervix between HIV-positive women receiving cryotherapy versus LEEP over 3 weeks of follow-up.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCervical Intraepithelial Neoplasia
CountriesKenya
CollaboratorsUniversity of Nairobi, International Agency for Research on Cancer

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedFeb 17, 2011
Enrollment StartJun 1, 2011
Primary CompletionOct 1, 2016
Study CompletionJan 1, 2017
TodayJul 2, 2026
Enrollment to primary: 5.3 yearsPosted 15.4 years ago

Interventions

Loop Electrosurgical Excision Procedure (LEEP)procedure

LEEP procedure uses a low-voltage electrified wire loop to cut out diseased part of cervix

Cryotherapyprocedure

Cryotherapy procedure involves using a cryoprobe and carbon dioxide or nitrous oxide gas to freeze the diseased part of the cervix