CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 413 enrolled
Drug / intervention
Exercise Behaviour Maintenance +2 morebehavioral
Likely dose
Not stated in record
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Search/NCT01305447
NCT01305447Phase 2Completed

Getting Physical on Cigarettes: Exercise and Smoking Cessation - Preventing Relapse

University of Western Ontario, Canada·interventional·Posted Feb 28, 2011·Updated Dec 16, 2014

In Brief

A Phase 2 clinical trial evaluating Exercise Behaviour Maintenance, Smoking Relapse prevention booklets, and 1 other intervention for Cancer. Completed, enrolled 413 participants across 1 site.

Detailed Summary

Adult female smokers will participate in an exercise-aided smoking cessation program, and will then be randomized into one of four cessation maintenance conditions: (a) Exercise Maintenance only (b) Exercise Maintenance + Relapse Prevention Booklets(c) Relapse Prevention Booklets + Contact and (d) Contact Control. Primary follow-up outcome is smoking behaviour. Secondary outcomes include exercise behaviour, Physiological measures (body composition (Dual-emission X-ray absorptiometry; DXA), vascular health (stiffness, endothelial function, carotid plaque volume), physical fitness), and Psychological measures (self-regulatory cognitions related to exercise adherence \[exercise, scheduling, barrier, relapse, and concurrent self-regulatory self-efficacy\]). The hypotheses detailed below are specific to the randomization of participants into the following 4 groups: 1. Exercise Maintenance only 2. Exercise Maintenance + Relapse Prevention Booklets 3. Relapse Prevention Booklets + Contact 4. Contact Control Hypothesis 1: Compared to quitters in the contact control condition, quitters exposed to a home-based lifestyle exercise maintenance intervention (Exercise Maintenance only and Exercise Maintenance + Relapse Prevention Booklets) will demonstrate significantly greater exercise adherence and fitness levels, as well as significantly less weight gain and smoking relapse rates following exercise-aided smoking cessation program termination. Hypothesis 2: Compared to quitters in the contact control condition, quitters exposed to relapse information only (Relapse Prevention Booklets + Contact) will experience significantly less smoking relapse following exercise-aided smoking cessation program termination. Due to the novelty and exploratory nature of the respective prevention programs, no hypotheses are specified with respect to which prevention program (exercise maintenance or relapse prevention information) will be superior to the other, or whether the additive benefits (i.e., exercise maintenance plus relapse prevention information) will be superior to one prevention program alone.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCancer
CountriesCanada

Timeline

Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedFeb 28, 2011
Enrollment StartOct 1, 2009
Primary CompletionApr 1, 2014
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 15.3 years ago

Interventions

Exercise Behaviour Maintenancebehavioral

Following the termination of the 14 week exercise aided smoking cessation program, trained exercise facilitators will deliver 15 minute biweekly (for the first month), monthly (for the next 2 months), and then bimonthly (for last 8 months) phone calls to remind the participants of the self-regulatory skills they learned during group discussion.

Smoking Relapse prevention bookletsbehavioral

Participants will be given Brandon et al. (2000, 2004) smoking relapse prevention booklets following exercise program.

Contact controlbehavioral

No treatment, but equal contact time as the other intervention arms. Topics of women's health, unrelated to exercise will be discussed in group-mediated sessions(control).