CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 120 enrolled
Drug / intervention
midazolam +3 moredrug
Likely dose
midazolam 7,5mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01309360
NCT01309360Phase 4Completed
CompareCT.gov

Ultrasound-guided Block of the Brachial Plexus Using Prilocaine: Effects of Local-anesthetic Dose Reduction on Parameters of Block Quality and Adverse Effects in Outpatients

Helios Research Center·interventional·Posted Mar 7, 2011·Updated Jul 12, 2011

In Brief

A Phase 4 clinical trial evaluating midazolam and prilocaine 1% for Other Surgical Procedures. Completed, enrolled 120 participants.

Detailed Summary

Clinical aim: Does reducing the dose of local anesthetic in ultrasound-guided axillary plexus anesthesia have any effect on the success rate and additional parameters of block quality? Methodology: In this prospective cohort study three groups of 40 outpatients each were administered dosages of 1% prilocaine of either 40mL, 30mL or 20mL for axillary plexus anesthesia. Met-Hb was measured prior to administration of the block and then hourly until the Met-Hb concentration fell. Parameters of block quality and any adverse effects were recorded. The level of significance was defined with α ≤ 0.05.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOther Surgical Procedures
Countries--
Collaborators--

Timeline

Phase 4CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedMar 7, 2011
Enrollment StartSep 1, 2009
Primary CompletionApr 1, 2010
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 15.3 years ago

Interventions

midazolamdrug

Prior to performing the regional anesthesia the investigators administered midazolam as a premedication by mouth (3,75-7,5mg) or intravenously (2-3mg).

prilocaine 1%drug

40 outpatients : 40ml prilocaine 1% were administered for axillary plexus block

prilocaine 1%drug

40 outpatients : 30ml prilocaine 1% were administered for axillary plexus block

prilocaine 1%drug

40 outpatients : 20ml prilocaine 1% were administered for axillary plexus block