CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 12 enrolled
Drug / intervention
Roux-en-Y gastric bypass (RYGBP)procedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01317147
NCT01317147N/ACompleted
CompareCT.gov

The Effect of Gastric Bypass on the Pharmacokinetics of Serotonin Reuptake Inhibitors

University of Pittsburgh·observational·Posted Mar 17, 2011·Updated Mar 17, 2011

In Brief

An observational study evaluating Roux-en-Y gastric bypass (RYGBP) for Gastric Bypass and 2 related conditions. Completed, enrolled 12 participants across 1 site.

Detailed Summary

The morbidly obese frequently present with mood and anxiety disorders, which are often treated with serotonin reuptake inhibitors (SRI) antidepressant drugs. The investigators hypothesized that gastric bypass surgery would decrease the absorption of SRI. The investigators also wished to determine whether a reduction in SRI levels would increase the likelihood of worsening depressive symptoms.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsGastric Bypass, Depression, Anxiety Disorder
CountriesUnited States
CollaboratorsAmerican Society for Metabolic and Bariatric Surgery

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 17, 2011
Enrollment StartAug 1, 2007
Study CompletionAug 1, 2010
TodayJul 2, 2026
Posted 15.3 years ago

Interventions

Roux-en-Y gastric bypass (RYGBP)procedure