CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 10 enrolled
Drug / intervention
Coenzyme Q10 +1 moredrug
Likely dose
Coenzyme Q10 200mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01319110
NCT01319110Phase 2Completed
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Coenzyme Q10 in Post-Cardiac Arrest Cerebral Resuscitation

Beth Israel Deaconess Medical Center·interventional·Posted Mar 21, 2011·Updated Jul 31, 2017

In Brief

A Phase 2 clinical trial evaluating Coenzyme Q10 and Placebo for Cardiac Arrest and Sudden Cardiac Arrest. Completed, enrolled 10 participants across 1 site.

Detailed Summary

Specific Aim #1: To determine if levels of CoQ10 are low post-cardiac arrest (CA). We will perform a prospective trial with the primary endpoint of describing the prevalence of low serum CoQ10 levels. Specific Aim #2: To determine if CoQ10 levels in post-CA patients can be increased with the administration of exogenous CoQ10.. We will perform a randomized control trial (RCT) of post-CA patients with the secondary endpoint of comparing CoQ10 levels among those randomized to CoQ10 supplementation vs placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCardiac Arrest, Sudden Cardiac Arrest
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedMar 21, 2011
Enrollment StartFeb 1, 2011
Primary CompletionDec 31, 2011
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 15.3 years ago

Interventions

Coenzyme Q10drug

Patients will receive CoQ10 200mg three times per day for 7 days, until return to baseline neurologic status, or until death/discharge (whichever comes first). CoQ10 will be given through pre-existing NG or OG tube, and mixed with 20 ml of chocolate Ensure so as to blind investigators and staff.

Placebodietary

Patients will be given Chocolate Ensure via NG/ OG 3x daily as a placebo.